We often hear that fish oil is good for this. Or that.
But we still don’t know a lot about HOW the Omega-3 in fish oil actually makes these health benefits happen.
Sure, we know for certain that Omega-3 reduces triglycerides. After all, the FDA approved drug Lovaza is pharmaceutical grade fish oil. And it’s used to treat familial hypertriglyceridemia, an inherited condition in which people have very high triglycerides.
Fish oil reduces triglyceride by doing the following:
- Reduction of VLDL production by the liver
- Ramping up the removal of VLDL from the blood
VLDL (very low density lipoproteins) are rich in triglycerides and since fish oil exerts its influence on VLDL, you will notice a difference in the triglyceride levels. Reference here.
But what about other health conditions?
Fish oil is very important to eye health. After all, there is a lot of Omega-3 stored in your eye balls.
Recently, researchers from Children’s Hospital in Boston figured out how Omega-3 helps prevent retinopathy.
Retinopathy is a disease where leaky blood vessels in the retina causes blindness. It’s one of the leading causes of blindness, affecting over 4 million Americans, especially if you have diabetes.
Omega-3 is highly concentrated in the retina.
Here’s what the researchers found about the actual biological MECHANISM of how fish oil helps with eye health:
- Omega-3 decreased inflammatory messaging in the eye
- Omega-3 promotes the growth of healthy blood vessels and limits the growth of abnormal blood vessels.
The researchers found that a compound called 4-HDHA, made from Omega-3 DHA is responsible for this.
That was not the only discovery.
They also found that taking more Omega-3 helps improve insulin sensitivity for those battling diabetes or pre-diabetes.
Now, the researchers are going to turn their attention to harmful Omega-6 fatty acid and its byproducts.
“We found the good guys, now we’ll look for the bad ones,” said Dr. Lois Smith.
Other Fish Oil & Eye Health Studies
You may have heard of AREDS. It stands for Age Related Eye Disease Study.
It’s an ongoing study that is evaluating the addition of lutein, zeaxanthin and EPA + DHA Omega-3 in preventing eye disease. The results are not ready for release, but visit their site here to find out more.
Stay tuned – I’ll report any findings here as soon as they are published.
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About the Author: Vin Kutty, MS, is co-founder of Innovix Pharma. He is a nutritionist, author, and Omega-3 expert with 20 years of experience.